Distress and/or dysfunction are well established as key reasons for help-seeking.
Metrics were established as key performance indicators to assess progress toward the stated goals of (1) optimizing content to enhance patient-centeredness, (2) enhancing reach and engagement, and (3) maintaining sustainability.
Effector and memory CD8+ T cells are well established as key mediators of tumor cytotoxicity, but the roles of CD4+ T cells in tumor microenvironments have not been as extensively explored.
To determine if the improvements in wound healing and reduced hyperactivity resulting from Nestlet treatment were associated with changes in neural activity, we examined gene expression in the hippocampus and mPFC, regions having been established as key to the stress response [40], [41].
During the evolution of multicellular organisms, antimicrobial peptides were established as key elements of innate immunity.
Evolutionarily conserved high-abundance miRNAs are becoming established as key players in the etiology of human cancers.
The heterotrimeric G-proteins have been well established as key regulators of neuronal growth, differentiation, and function.
These structures have been established as "key brain regions" in the pathophysiology of OCD [ 3, 5, 27, 42, 43].
