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The 0.2 μg/ml tunicamycin concentration has been used widely in the field as it has been empirically established as a concentration at which ER stress is tolerable to WT cells but toxic to UPR mutants.
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Inhaled formaldehyde at sufficient concentrations has been established as a carcinogen for nasal tumors in rodents, with numerous studies documenting this phenomenon.
Intermittent oral administration of calcitriol has been established as a means of achieving potentially therapeutic peak concentrations.
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Architecture is established as a profession.
LOQ was established as the concentration of the standard compound equalling 10× of the baseline noise.
The limit of quantitation (LOQ) was established as the lowest concentration of an analyte in a sample that can be determined with acceptable precision and accuracy under the stated conditions of test [37].
Minimum inhibitory concentration (MIC) was established as the lowest concentration of compound able to inhibit the visible growth of microorganism after overnight incubation.
The optimum conditions were established as: concentration of ascorbic acid (VC) and H2O2 17.26 mM, degradation temperature 51 °C and degradation time 1.6 h.
For the azoles such as fluconazole, itraconazole and ketoconazole, the MIC was established as the lowest concentration that inhibited 80% of the control growth.
The LLOQ was established as the lowest concentration of YH-8 in the calibration curve at which precision was within 20% of the relative standard deviation (RSD) and accuracy was between 80% and 120% of the theoretical value.
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