Sentence examples for established ability of from inspiring English sources

Despite the established ability of T4 immunotherapy to elicit cytokine release syndrome in SCID Beige mice, therapy was very well tolerated.

In light of the previously established ability of IL-27 to inhibit HIV replication4,5, the impact of IL-27 on BST-2 expression may represent an additional mechanism by which IL-27 can accomplish this function; this is of particular importance if recombinant IL-27 was to be considered as a potential adjunct to anti-retroviral therapy.

These observations are consistent with the established ability of mutator alleles to accelerate adaptation in novel environmental conditions [7], [36].

Perhaps of greater importance is the established ability of GLP-1 to stimulate cAMP production and to activate both PKA and Epac [19], [20].

The superior performance of hNPCctx-GDNF is consistent with both the known role of GDNF as a neuroprotective molecule within the retina [25] [30] and the established ability of hNPCctx to function as a cell-based drug delivery vector in diverse CNS tissues [11], [12].

This made use of the established ability of such termination sequences to reduce transcription initiated from promoters other than the target.

In light of their established ability to span reconstituted membranes, we postulated that the pores could be adapted and exploited to puncture biological cell membranes.

The explanation may lie in the well-established ability of nerve tissue to concentrate folate to a level of about five times that in the plasma.

For instance, the well-established ability of many brain tumors to widely diffuse into surrounding normal parenchyma frequently precludes complete surgical resection.

It seems unlikely that SNC80-induced internalization simply replaced constitutive internalization exactly, yet this result does not, at first, seem to agree with the well-established ability of SNC80 to induce DOP receptor internalization (Pradhan et al., 2010).

Here, as suggested in Ref. [ 33], the well-established ability of OCT to visualize micromorphological features of the retina could be complemented by absorption contrast of PA imaging to quantify retinal blood oxygenation and specific chromophores such as melanin in the RPE.