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Using a variety of vinculin mutants, we establish which components of the cell-matrix adhesion network are coordinated through direct and indirect associations with vinculin.
However, using RCTs is difficult when implementing complex interventions involving multiple components since it is not possible to 'blind' providers or recipients to the control and intervention groups and it is also difficult to establish which components of a complex intervention worked and which did not.
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An empirical linear relationship between KD and soil properties: pH and total metal content were also employed to establish which component contributed most in solubility of the trace elements.
Lastly, even if causal risk factors are identified, the potential benefits of this research will only be realized if it is followed by attempts to establish (a) which components of the risk syndrome are modifiable, and (b) how these can be altered through interventions (Eaton et al. 1995; Mrazek and Haggerty 1994).
There is considerable variability in outcomes between participants of efficacious interventions, and it is important to establish which intervention components were most critical for behavior change.
Given that our intervention was multimodal, it is not possible to establish which of the individual treatment components was more or less effective or which contributed to each of the outcomes observed.
Further experiments are required to establish which proportion of the induced miR164 accumulation is due to the transcriptional effect, which is the precise mechanism involved and to uncover which is the biological relevance of this transcriptional component.
Assessment of feasibility determines whether the intervention can be successfully implemented to establish actual exposure to the intervention as it was intended, and to examine which components of the intervention were successful and which ones were not [ 121].
The purpose of the process evaluation is to establish actual exposure to the intervention as it was intended, and to examine which components of the intervention were successful and which ones were not.
Which components of the programme are meaningful?
We have to establish which it was".
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com