To investigate changes in the frequency of participation 6 months poststroke compared with prestroke; and to establish whether the change is associated with participation restrictions and satisfaction with participation 6 months poststroke.
The presence of a structural brain change in this disorder provides an impetus to further research to establish whether the change is pathological or iatrogenic and whether it may be of diagnostic utility.
Because there is no a priori way to predict whether any one of the identified synonymous and noncoding somatic alterations disrupts function, analysis unique to each gene will be required to establish whether the change is functional.
We aimed to establish whether the change in one intervention was significantly greater than the control group over the 12 month follow-up that is, ifollow-up thate lisear contrasts (rather than quadratif contretrospectiveignificant, which woulinearicontrastsge overather rathan than just a difference at one time point.
Although some miRNAs have been shown to exert a disruptive effect on skeletal muscle differentiation at least in cell culture models [ 70], in most cases, it remains to be established whether the changes in miRNA expression levels are causally involved in these diseases or are secondary to the degeneration/regeneration response of the affected muscle tissue.
To establish whether the observed changes in APP, tau and TXN protein levels in hippuristanol treated cells were due to changes in new protein synthesis rather than turnover, synthesis rates were measured by immunoprecipitation following 35S-methionine labeling of SH-SY5Y cells (figure 2B).
Longer term studies are needed to establish whether the structural changes and behavioral deficits found in the mice last, Stanton says.
To establish whether the observed changes translates into improved performance at the whole plant level, growth rates were determined for the lines at various temperatures.
A final limitation is the fact that it is difficult to establish whether the observed changes in liver mitochondrial respiration are a result of the increased blood pressure or a direct effect of the compound norephinephrine.
When available, parental DNAs were sequenced to establish whether the identified changes in sporadic cases were de novo or to confirm cosegregation between the variant and phenotype in families transmitting the trait.
