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who understood the nature of the study and were fluent in both Korean and English held an expert reviewers' meeting to establish translation validity.
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The ENAT was translated into Dutch using an established translation methodology [ 12], which comprised the following stages: An initial forward translation was undertaken by two independent bilingual translators (CD and IB) whose mother tongue was the target language (Dutch).
Unlike hemodynamic and cardiac electrophysiological methods, which have been routinely used in drug safety testing for years, the non-clinical assessment of drug effects on myocardial contractility is used less frequently with no established translation to humans.
A standard Chinese version of Leicester cough questionnaire (LCQ) was developed by an established translation procedure and its repeatability was assessed in a preliminary study involving 20 untreated patients with stable chronic cough.
To establish how translation was regulated in myo1Δ strains, we analyzed two common mechanisms for down regulation of translation initiation described in yeast.
Large-scale clinical studies are needed to establish the translation of pre-clinical findings to the clinical arena.
These results firmly establish that translation is defective in these embryos and can be improved with l-leucine.
Our data show that ADAC mitigates noise-induced hearing loss in a dose- and time-dependent manner, but further studies are required to establish its translation as a clinical otological treatment.
The active metabolism of cofactors and vitamins may help to establish the translation process; the biosynthesis of the secondary metabolites discussed above might help to re-establish the osmotic balance and reduce the threat of ROS, and the biodegradation of xenobiotics might help remove injurants generated or introduced by salt stress.
However, this is an aggressively conservative waning profile and data from larger phase III studies is needed to establish the translation of protection against incident infection into prevention of persistent infection and precancerous lesions and the durability of protection for non-16/18 non-16/18.
Inhibitors of eukaryotic translation have entered the clinic, establishing the translation machinery as a promising target for chemotherapy.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com