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There is a clear need to establish tool interoperability as it enables new types of analyses, facilitates new applications, and promotes interdisciplinary collaborations [14].
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It is highly desirable, both clinically and economically, to establish tools to distinguish responders from nonresponders and to predict possible outcomes of the IFN-alfa/RBV treatments.
Demographic monitoring is a well established tool for conservation managers.
Principal Component Analysis (PCA) is a well established tool for dimensionality reduction.
Structure-based virtual screening is currently an established tool in drug lead discovery projects.
Human biological monitoring (HBM) is a well established tool in occupational and environmental medicine.
For this purpose, mathematical modeling is the theoretically established tool to analyze such systems.
Shooting methods are a well established tool for the numerical solution of terminal value problems of fractional order.
Mathematical modelling is the theoretically established tool for developing solar heating systems, e.g. with using transfer functions.
Mathematical modelling is the theoretically established tool for it, for example with using the collector transfer functions.
In pharmaceutical modelling, cellular automata have been used as an established tool to represent molecular changes through discrete structural interactions.
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