Sentence examples for establish the involvement from inspiring English sources

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Further investigations were therefore directed to establish the involvement of FOXO3a transcription factor localization and Akt activity, both of which are involved in p21/CDKN1A expression [ 28, 29].

In this respect, our findings showing that the remaining vasopressor responses to DHE after ritanserin-pretreatment were attenuated by 10 and 30 μg/kg prazosin (Fig. 4a) and that they were markedly blocked by 100 and 300 μg/kg rauwolscine (Fig. 4b) establish the involvement of rauwolscine-sensitive α2-adrenoceptors and, to a lesser extent, of prazosin-sensitive α1-adrenoceptors.

We tried to establish the involvement of membrane-associated proteins in STPK mediated signaling.

To determine whether the bipartite conditional gene expression system could be used to establish the involvement of the p38 MAPK pathway during the differentiation of myocytes from human adults, we deployed the p38α/β-specific inhibitor SB 203580 or shRNAs targeting p38α transcripts.

Together, these observations establish the involvement of TBP2 in transcription initiation of oocytes.

These results further establish the involvement of prenylated proteins, and more specifically the Rho-mediated signaling pathway, in the negative regulation of ER transcriptional activity.

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Animal models and clinical studies established the involvement of glutamate and GABA neurotransmission in drug addiction.

Strouhal et al. (2003) have also established the involvement of proteins with heavy metal binding, sequestration and bioaccumulation in Yarrowia species.

The small but negative heat capacity change of the analogs along with the significant enthalpy entropy compensation phenomenon observed established the involvement of multiple weak noncovalent interactions in the binding process.

Verapamil abrogated the acquisition of chemoresistance (Figure 4C), thus establishing the involvement of MDR proteins.

A number of studies have also established the involvement of MAPKs in stem cell senescence.

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