For instance, the initial KR domain of the Pik PKS (KR1) reduces the β-ketone to an alcohol, which establishes the configuration at C-11 of methymycin and C-13 of pikromycin.
To establish the relative configuration, an X-ray experiment was evolved, which suggested the relative configuration of H-4, H-5, H-6, H-8, H-12, and H-15 to be α, α, β, α, β, and β, respectively (Fig. 4).
If two people arrive together one of them must establish the network configuration.
It is the first time to establish the absolute configuration of lyconadin-type Lycopodium alkaloid by an X-ray diffraction experiment.
Widdowson was the first to establish the absolute configuration of 4 and employ it in [4+2] cycloadditions [18] and Mihovilovic subsequently reported tethered cycloadditions [19, 20].
The proposed solution is investigated in order to establish the optimum configuration and the performances in case of the South-East part of the Europe conditions.
Numerical simulations are performed to investigate the electrokinetic transport processes in the microfluidic device and to establish the optimal configuration of the expansion chamber.
Based on the proposed model, we analyze the performances of the device varying with the resonant levels and half widths of two energy filters and establish the optimal configuration of the cooling device.
Response surface methodology (RS M was employed in parallel with the finite element models to perform both parametric studies and multi-objective optimization in order to establish the optimal configuration of the sandwich tube.
The first step of the model comparison was to establish the best configuration (A vs. B vs. C vs. D) for the modulatory effects between aOT and PrC.
