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Some of the main elements of teaching via problem solving include (a) providing students with enough information to let them establish the background of the problem, (b) encouraging students to make generalizations about the rules or concepts, and (c) reducing teachers' role to providing guidance during the solution process (Evan & Lappan 1994).
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Each episode of "Black Mirror" establishes the background of normality against which a decisive tweak will stand out all the more starkly.
Because tamoxifen is associated with endometrial pathology, the ATAC endometrial subprotocol was initiated to establish the background prevalence of pathology, and to assess prospectively the incidence and nature of intrauterine changes before and following endocrine therapy.
Substrate subjected to PMCA but lacking TSE agent seed did not contain detectable PrPres and samples containing TSE agents that were not sonicated establish the background levels of PrPres.
To establish the background allele frequency of variants identified in this study in a UK control population, we utilised a subset of the British Birth Cohort of 1958 (n = 350 for the intronic variants identified, n = 1050 for the exonic variant identified) [16], [17].
However, in view of the small but significant differences in genome sequence as reported earlier, it was important to establish the genetic background of our strain to assess correctly the phenotype of the above-mentioned mutants.
Due to the rising absolute number of MDR 19A isolates, MLST was performed to establish the genetic background of these strains.
In spite the fact that chronic periodontitis is a risk indicator for peri-implantitis, previous studies including genetic analysis of peri-implantitis did not differentiate patients with or without chronic periodontitis in order to establish the genetic background of peri-implantitis by itself.
Transgenic fly lines carrying the human Aβ42 was established in the background of the Canton-S w1118 (isoCJ1) genotype as described in [14].
Transgenic fly lines carrying hs-dCREB2d, UAS-dCREB2b, CRE-luciferase flies were established in the background of the Canton-S w1118 (isoCJ1) genotype [25].
Our results establish that in the background of Q151Mc, K70Q causes TFV resistance through a third mechanism: by decreasing the binding affinity of the inhibitor (Kd-dependent exclusion mechanism).
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