Although the impact of the survival surgery protocol in the TNBS-treated group was not controlled for in the healthy control group in our study, other studies using the same established surgery protocol and sham treatment revealed a minimal impact of the procedure in itself on these animals [ 25, 27, 29, 30].
Although the role of surgical resection for multiple brain metastases has not been established, surgery has been performed in cases with large lesions or significant mass effects and in cases where two or more lesions are accessible through a single craniotomy approach [ 16].
Although the role of surgical resection for multiple brain metastases has not been established, surgery could be tried in cases with large lesions or significant mass effects and in cases where two or more lesions are accessible through a single craniotomy approach [ 14].
The trial aims to establish whether surgery yields superior results to non-surgical treatment.
It is well established that surgery, especially gastrointestinal cancer surgery, in nonbleeding cirrhotic patients carries a high risk of mortality and morbidity.
Novel therapeutic approaches, such as gene therapy, often complement established ones: surgery, chemotherapy or radiotherapy.
In the remaining 76,416 patients who underwent one surgery only in this period, it was necessary to establish whether the surgery corresponded to first-eye surgery without a second surgery before December 2002 or second-eye surgery with the first eye being operated on prior to January 1999.
Endoscopic approach is nowadays well established in surgery of chronic rhinosinusitis (FESS, functional endoscopic sinus surgery) as well as in treatment of benign sinonasal diseases.
First of all, the criteria used (surgeon's opinion and CT very early after surgery) to establish whether or not a resection was complete.
