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The observed values were then clustered to establish null expected values for Theta and R for AA, AB, and BB states.
GO analyses were performed as described above with the exception that human default GO term frequencies were used to establish null expectations (EASE score p < 0.02).
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The overall FNR was 2.56 %, with a 95.03 % CI of 0.06 13.49; thus, the prospectively established null hypothesis was rejected in favor of the alternative hypothesis (p = 0.0205).
To unequivocally define the role of Shp2 in regulation of mESC activities, we sought to establish Shp2 null mutants.
The one-ratio model analysis, which assumes an equal ω value among all branches, was first conducted to establish the null hypothesis [ 63].
These scrambled data were used to establish a null distribution describing the strength of statistical association which could be expected from data with the same marginal distributions (i.e. those arising by chance), in the absence of any spatial information.
If the MID is truly to be the smallest effect considered meaningful, however, it would be logical to establish the null hypothesis to rule out a difference less than or equal to the MID.
These findings establish Ugt1-null mice as a versatile model in which to study bilirubin neurotoxicity and potential treatments for hyperbilirubinemia.
The intention of these experiments was to establish a null-model for the sequence of decay of characters, not to mimic the process of fossilization, and as such the minimum number of experimental variables was used.
Moreover, the full allelic configuration of the mapping parents could be established, including null alleles, homozygous loci, and alleles that were present on multiple homoeologues.
Therefore, the techniques for establishing suitable null models and randomization procedures need to be developed further, before making any statements about their biological importance.
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CEO of Professional Science Editing for Scientists @ prosciediting.com