Sentence examples for establish cohesion from inspiring English sources

Upon entry into S-phase, as the sister chromatids are being synthesized, the two establishment of cohesion factors, ESCO1 and ESCO2, establish cohesion by securing the cohesin ring around sister chromatids (Skibbens et al., 1999; Hartman et al., 2000; Homer et al., 2005; Skibbens, 2009; Terret et al., 2009).

Both Smc3 acetylation and Scc1 acetylation appeared to counteract the function of Wapl to establish cohesion.

Cohesin-DNA complexes in eco1∆ wpl1∆ cells are stably bound to DNA but fail to establish cohesion, indicating a post-DNA binding step is required for cohesion.

Yeast cells that fail to establish cohesion in S phase are unable to repair damage caused by γ-irradiation (Sjogren and Nasmyth 2001).

Cohesin that is not deacetylated in anaphase, or a mutant version that mimics this state, loads onto chromosomes in the next cell cycle, but fails to establish cohesion.

Thus, programmed meiotic DSBs are essential for COH-3/4-dependent SCC, and the kleisin subunit determines whether a cohesin requires DSBs to establish cohesion.

Cohesin is loaded on chromatin in early G1 in vertebrate cells and establishes cohesion during S phase [4], [5].

In budding yeast, the acetyltransferase Eco1/Ctf7 establishes cohesion during DNA replication in S phase and in response to DNA double strand breaks in G2/M phase.

Ctf7 establishes cohesion during S phase, and interacts with components of the DNA replication machinery, including PCNA and RFC [ 5- 7].

Only 63% mps3 ∆ pom152 ∆ cells established cohesion, which is similar to the amount of cohesion observed in mps3 ∆75–150 mutants (64%) (Ghosh et al. 2012).

Consistent with this idea, cohesin, which established cohesion in S phase, has been reported to be removed genome-wide upon DNA damage in G2/M (McAleenan et al. 2013).