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Our results confirm with unequivocal genetic approaches that RA and RARα perform essential non-transcriptional functions in regulating synaptic strength, and establish a functional link between the various domains of RARα and their involvement in regulating protein synthesis and excitatory synaptic transmission during homeostatic plasticity.
Our recent findings establish a functional link between foreign nanosized bodies and autophagy.
Thus, the similarity in the ligand-binding sites helps establish a functional link between the two proteins.
In order to establish a functional link between these phenomena, we investigated the effect of GYS1 interference on hypoxia-induced glycogen accumulation.
Our recent results provide a novel mechanism for CXCR4-mediated tumor growth and metastasis and establish a functional link between CXCR4/CXCL12 and CCR6/CCL20 pathways in tumor development.
TGF-β signaling crosstalk with the ephrin pathway may contribute to the anabolic and anti-catabolic effects of SD-208 on bone, though additional experiments are needed to establish a functional link.
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We established a functional link for each pair of proteins that are part of the same complex.
Previously, we established a functional link between HIF-1α-controlled reduction of ROS and anchorage independence of gastric cancer cells [22], implicating HIF-1α in the pathogenesis of gastric cancer in the absence of hypoxia.
TSC2 is required for the normal trafficking of PC-1 from the Golgi to the membrane [23] and more recently, PC-1 was also shown to interact with TSC2 [22], establishing a functional link between these two proteins.
This finding establishes a functional link between the flexible loop and chemical barrier crossing.
Both proteins play roles in transcriptional repression, and expression analysis in yeast Tail mutants has established a functional link between them (van de Peppel et al., 2005 ).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com