Sentence examples for essentiality to the from inspiring English sources

Interestingly, successive modification of the ITO surface with aminopropylsilane and disuccinimidyl suberate, of which essentiality to the potential response to indole compounds we previously reported, improved the stability of the rest potential and enabled the electrodes to respond to tryptophan in case of specimens with Ra values ranging between ∼2 and ∼3 nm but not for those with Ra of ∼1 nm.

The targetablity of a drug target depends on several factors which include: essentiality to the growth and survival of the pathogen, non homologous to the host, availability of 3D structure and gene expression: a target would be desirable if it is expressed in the organism at least under disease conditions.

We ranked those bridges according to their sufficiency rating (SR): a percentage from 0 (worst) to 100 (best), which is determined by a government formula that factors in a bridge's structural adequacy, safety, serviceability for modern use, and essentiality to the public.

Due to this specificity and essentiality to the limitless lifespan of cancer cells, telomerase is considered a valid and attractive anticancer target [4].

An important implication of the core proteome is its essentiality to the set of bacteria studied and to the bacterial domain as a whole.

Here we test whether the different prokaryotic ancestries of human genes have an effect on phenotype, essentiality to the organism, selective constraint, function, expression level and breadth, and position of the encoded products in the PIN.

To assign the probability of essentiality to all genes, the following procedure was used.

It is also possible to envision certain scenarios where drugs affecting parts of the metabolic network induce essentiality to uninhibited enzymes in the network.

In particular, we tested the extent to which exchange fluxes from ccRCC cell lines can be used to infer gene essentiality attributable to the ccRCC phenotype.

In the analysis of iMM904, the statistical classification function, specificity and sensitivity, were employed in the analysis of the essentiality simulation to represent the proportion of negative and positive (lethal and viable) phenotypes correctly predicted as negative and positive, respectively (Table 1).

A more thorough approach to determine essentiality at the DNA level is using an approach based on the "plasmid shuffling" approach established in yeast.