Sentence examples for essential to exert a from inspiring English sources

Therefore, activation of MC3R is essential to exert a tonic inhibitory action during the inflammatory response that occurs in this experimental model.

The presence of enteral lipids is essential to exert these protective effects.

The presence of resveratrol in the grape nutraceutical appeared essential to exert these effects.

These findings contradict the suggestion that maternal tissues are essential to exert mechanical forces that enable DVE formation.

40 Taken together, these data indicate that both the C2 and phosphatase domains might be essential to exert phosphatase activity and negatively regulate TGFβ‐induced EMT.

For instance, in breast cancer cells SIRT1 was shown to exert an essential role toward the oncogenic signaling mediated by the estrogen receptor- α (ER α).

Since Myc has been shown to exert an essential role in B-cell homeostasis [ 24], we further analyzed how Myc may control B-cell fate in response to BCR triggering.

This loss of tumor-suppressive effect of Wnt5a was restored by expressing Daple-WT but not by expressing the Daple-FA mutant, indicating that a functionally intact GBA motif in Daple is essential for Wnt5a to exert its tumor suppressive effects.

Unfortunately, none of the obvious candidate cysteines seemed to be essential for ebselen to exert its action.

These findings strengthened the hypothesis that the phosphatase domain involves the essential regions required to exert protein phosphatase activity.

PTEN has been shown to be essential for SPRY2 to exert its inhibitory effect in EGFR-mediated signalling (Edwin et al, 2006).