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But it will be hard to sell to a shocked EU leadership, many of whom feel it is essential to demonstrate that departure is not a pain-free option.
In other words, before a military strike, it is essential to demonstrate that Iran was not prepared to accept a civil nuclear power capability with the kind of limitations that would prevent it from being able to produce nuclear weapons on short notice.
In efficacy studies, it is essential to demonstrate that a facilitator can implement the PD program with fidelity, in order to argue that any demonstrated impact (or lack thereof) is a true reflection of the PD program and cannot be attributed to implementation failure (Carroll et al. 2007; Raudenbush 2007).
But before undertaking one, it is essential to demonstrate that the likely benefits of using military force will outweigh the costs and produce better results at less cost than other policies.
For CTCs to fill this important niche, it is essential to demonstrate that they share molecular characteristics with a patient's solid tumor masses and that biomarker status in CTCs is reflective of biomarker status in neoplastic cells within tumor masses.
Since the parental cells used for the establishment of the AR cell line are not of prostate origin [45], it is essential to demonstrate that the overexpressed AR functions in a manner similar to the AR in its intact cellular environment.
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Therefore at the University of Western Sydney (UWS), it was defined, in the local context, as "the fundamental components of a course or unit, that are essential to demonstrate the capabilities, knowledge and skills to achieve the core learning outcomes of the course or unit, while preserving the academic integrity of the university's learning, assessment and accreditation process.
Although "vast demonstrations of solidarity will make little or no impression on the terrorists … it is essential to demonstrate as loudly as possible... that, for all the handwringing about western society's decadence, it retains core values of decency, compassion and tolerance".
74, 75 Nevertheless, partly as a result of the rosiglitazone experience, the US Food and Drug Administration FDAA) recognized the need for safety data and issued guidance in 2008 making it essential for manufacturers to demonstrate that a new antidiabetes therapy is not associated with an unacceptable increase in CV risk.
If Puerto Rico is to restore order with law, it is essential for the police force to demonstrate that it can do its job without breaking the law.
Genomic DNA fragmentation analysis was performed to demonstrate that essential oil induces apoptosis in human pancreatic cancer cells.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com