Sentence examples for essential role in sustaining from inspiring English sources
Therefore, it is suggested with these data that the transcriptional activity of Oct3/4 fluctuates in mESCs and that Oct3/4 plays an essential role in sustaining the basal transcriptional activities required for cell duplication in populations with equal differentiation potential.
Chemokines are also known to play an essential role in sustaining the inflammation associated with IIM.
CD4+ CD25+ FoxP3+ T cells (Tregs) play an essential role in sustaining self-tolerance by negatively regulating immune responses.
Systematic long-term sampling on a specific latitudinal band (equatorial region) also provides a unique opportunity to study the propagation of planetary-scale waves such as Kelvin waves and thermal tides, which might play essential roles in sustaining the super-rotation (e.g., Rossow et al., 1990; Yamamoto and Tanaka, 1997; Takagi and Matsuda, 2007).
Recent metagenomic studies of environments, such as marine and soil, have significantly enhanced our understanding of the diverse microbial communities living in these habitats and their essential roles in sustaining vast ecosystems.
The self-reactive CD4 T-cells play an essential role in triggering and sustaining organ-specific autoimmune diseases.
Of note, these factors play an essential role in creating an environment that sustains the tumor and its ability to metastasize.
Rho-kinase plays an essential role in regulating vascular smooth muscle (VSM) contraction, VSM cell proliferation, and migration [ 13], and sustained Rho-kinase mediated vasoconstriction seems to be closely associated with chronic hypoxia-induced pulmonary hypertension [ 14– 16].
Studies of mice provide early evidence that the gut microbiota has an essential role in energy harvest, in that germ-free mice need to consume approximately 30% more calories to sustain a body weight similar to conventionally raised mice [ 52].
Based on our finding that macromitophagy plays an essential role in preserving the mitochondrial network in CR yeast, we hypothesized that this form of selective macroautophagy is required for sustaining a healthy population of functional mitochondria in chronologically aging cells.
