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As discussed above, we proved TSC2 to be of essential relevance for these mTORC2-dependent regulations and TSC2 is very well known to exert its cell size effects via regulation of mTORC1/p70S6K.
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Firstly, given that a primary objective of preference-based HRQoL instruments is to measure health status at an individual level (albeit with health state values typically derived at the societal level), it is essential that such instruments have relevance for the intended respondents.
This chapter focuses on essential concepts that are of particular relevance for the design of immunotoxicity studies and the interpretation of results.
Complement is an essential component of the immune system and is of relevance for the destruction of invading microorganisms.
While deep phylogenetic information might be of little relevance for molecular epidemiology, unequivocal classification of bacterial strains is essential for many other applications.
A further essential insufficiency is their inconsistency with reality for very large values of the bubble coverage being of relevance for operation conditions leading to anode effects.
This has particular relevance for soccer.
This has specific relevance for artists.
Any culture finds a relevance for it.
I'd happily trade you relevance for information.
Its relevance for understanding China, therefore, is strictly limited.
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CEO of Professional Science Editing for Scientists @ prosciediting.com