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Discover Ludwig"essential regulators" is correct and usable in written English
You can use it to refer to something which is necessary in order to achieve a certain result. For example, "The government must implement new essential regulators to ensure the safety of the healthcare system."
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Inferred networks are strongly connected and do not fit a scale-free model, making it difficult to identify essential regulators using the hub-essentiality standard.
Microtubules are essential regulators of cell polarity, architecture and motility.
Small non-coding RNAs are essential regulators of gene expression at the transcriptional and posttranscriptional levels.
CDKs are valid targets as they function as essential regulators of cell growth and differentiation.
These studies provide a framework for studying crypt morphogenesis and identify essential regulators of niche formation.
Steroid receptor coactivators (SRCs) are essential regulators of nuclear hormone receptor function.
Because Cu, Co, and Mn are essential regulators of plant growth and development [24], they are clustered near each other in the nettle leaves.
Thus, the let-7 miRNAs of C. elegans and D. melanogaster both act as essential regulators for proper development at the larva-to-adult transition.
In this review, we summarize recent findings on miRNAs acting as essential regulators of ESCs and somatic cell reprogramming based on these categories.
Protein tyrosine phosphatases (PTPs) are essential regulators of signal transduction pathways, and control, together with protein tyrosine kinases (PTKs), the reversible phosphorylation of tyrosine residues.
Phosphoinositide (PI) 3-kinases are essential regulators of cellular proliferation, survival, metabolism, and motility that are frequently dysregulated in human disease.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com