Sentence examples for essential positive from inspiring English sources

HNF-4 was implicated as an essential positive regulator of HNF-1 alpha, as deletion of an HNF-4 binding site in the HNF-1 alpha promoter abolished promoter activity, and HNF-4 potently transactivated the HNF-1 alpha promoter in cotransfection assays.

The structures are a gated resistor turned off by depleting the channel (region II), when essential positive gate voltage is applied.

The major positive-charged crevice is located in the interface of N-lobe and C-lobe, in which K160, K171, R174, and K248 contribute the most essential positive charge.

"I'm confident that it will prove to be an essential positive for our city.

Firstly, although clock and cycle are the essential positive transcriptional regulators of the molecular clock in the fruit fly and mouse, diel expression of these genes differs between these groups [15], [16].

These results reveal an essential positive regulatory role of the cytoplasmic tail in CXCR4 signaling and suggest the tail is crucial for mediating G-protein activation and initiating crosstalk between G-protein-dependent and G-protein-independent pathways for correct GPCR signaling.

Play is essential to positive human development, but kids are playing less and less, says psychologist David Elkind.

Neilson JR, Winslow MM, Hur EM, and Crabtree GR. (2004) Calcineurin B1 is essential for positive but not negative selection during thymocyte development.

The photos have proven controversial, but the site claims "a bit of negativity is essential for positive change".

The LHCb RICH detectors are essential for positive kaon identification, and several strict demands are required of its photon detectors to achieve excellent particle identification performance.

Non-haematopoietic-cell MHC expression is essential for positive selection of regulatory T cells33, but this mechanism cannot readily explain the tolerance of autoreactive clones in mixed haematopoietic chimaeras, because the donor MHC is expressed only by haematopoietic cells.