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The VEGF family is an essential player in this process [ 4, 7].
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It is thus important to control cilia size and this study has identified Bug22 as an essential player in the determination of cilia size.
However, increasing evidence has shown that calcium is another essential player in the nitrate signaling network.
Taken together, p68 is shown to be an essential player in the regulation of H-Ras expression as well as in a vital transduction signal pathway tied to cell proliferation and many cancer processes.
It was found that when MDM2 levels in the knocked-down cells were reduced, PIR remained cytoplasmic even following treatment with proteasome inhibitors, indicating that MDM2 is an essential player in the nuclear localization of NLS-deficient PIR.
SIRT3 is thus an essential player in the mitochondrial glutathione antioxidant defense system [ 100].
One of the starch debranching enzymes, isoamylase (ISAI), is an essential player in the formation of crystalline amylopectin [ 18].
… a well-known APP, A2MG, is an essential player in the host response to sepsis and has therapeutic potential.
Pep4p is an essential player in the S. cerevisiae vacuolar proteolytic system, where it is important for both protein degradation and maturation of several vacuolar hydrolases.
The mitochondrial enzyme DLST is an essential player in the citric acid cycle that warrants proper adenosine-tri-phosphate (ATP) production.
A possible candidate for the DFNA47 locus is the transcription factor Nfib, an essential player in the maturation of lungs and brain development [ 30].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com