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However, increasing evidence has shown that calcium is another essential player in the nitrate signaling network.
Taken together, p68 is shown to be an essential player in the regulation of H-Ras expression as well as in a vital transduction signal pathway tied to cell proliferation and many cancer processes.
It was found that when MDM2 levels in the knocked-down cells were reduced, PIR remained cytoplasmic even following treatment with proteasome inhibitors, indicating that MDM2 is an essential player in the nuclear localization of NLS-deficient PIR.
SIRT3 is thus an essential player in the mitochondrial glutathione antioxidant defense system [ 100].
… a well-known APP, A2MG, is an essential player in the host response to sepsis and has therapeutic potential.
One of the starch debranching enzymes, isoamylase (ISAI), is an essential player in the formation of crystalline amylopectin [ 18].
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The VEGF family is an essential player in this process [ 4, 7].
Second, DST thinks that informational models of genes and gene action make it very tempting to attribute a kind of causal primacy to these factors, even when many other causal factors are essential players in the process in question.
Transient transcript alterations may be essential players in the ability of the cell to progress to a thermotolerant phenotype.
In addition, alveolar macrophages are also essential players in the initiation of ALI [ 11, 20].
Regardless, TET proteins as well as several other proteins (Table 1) are essential players in the demethylation of 5-mC.
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