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Problematic for drug design targeting ion channels is their vital role in normal cells for essential physiological functions.
Overall, this study suggests that lipid interactions play important roles in maintaining the essential physiological functions of caseins in mammalian milk.
Calcium signaling in the diverse vascular structures is regulated by a wide range of mechanical and biochemical factors to maintain essential physiological functions of the vasculature.
The class B family of G-protein-coupled receptors (GPCRs) regulates essential physiological functions such as exocrine and endocrine secretions, feeding behaviour, metabolism, growth, and neuro- and immuno-modulations.
The kidney vasculature has a unique and complex architecture that is central for the kidney to exert its multiple and essential physiological functions with the ultimate goal of maintaining homeostasis.
In addition to their role in gas exchange, the gills constitute organs of active, transepithelial, ion transport, an activity of major importance that underlies many essential physiological functions like osmoregulation, calcium homeostasis, ammonium excretion and extracellular pH regulation.
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However, sleep is an essential physiological function; a key research concept is that of 'social jetlag' - the difference between when our internal body clock wants us to get up in the morning versus when we are forced out of bed by our alarm clock.
The enzyme catalyzes an essential physiological function, the interconversion between carbon dioxide (CO2) and bicarbonate [ 26].
These data report for the first time an essential physiological function of flfl in maintaining tissue homeostasis and organ development.
The function of CA10 is the inter-conversion between carbon dioxide and bicarbonate, with essential physiological function in many tissues [ 65].
At face value, the low rate of retention of GbE among gnathostome lineages would seem to suggest that the gene is not performing an essential physiological function.
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