We therefore unexpectedly uncover a ROQUIN AMPK metabolic signaling nexus essential for selectively promoting Tfh responses.
Bernard Williams, a British moral philosopher who died in 2003, referred to that core as a person's "ground project," one's nexus of essential beliefs and desires.
The design of therapeutics targeting these essential cooperating TFs at the nexus of pathways fundamental to cancer progression might improve the chances of recovery for patients.
Integrating EBM teaching alongside bedside and other PBL and blended-learning approaches provides students with an opportunity to improve competence in both their EBM and clinical skills – a nexus that it essential if EBM is to be applied in the clinical setting.
Bridging these gaps is essential in assessing the water-energy-food nexus related to climate change and ecosystem processes.
As such, the NEXUS lenses were not only essential in advancing and unifying the NEXUS research agenda, but also became an important mechanism for enhancing external visibility and in establishing the NEXUS identity.
The recent health reform (2009 2011) in China articulated specific governance and incentive structures for public health organisations to address the issues of poor quality in prescribing, such as the enforcement of an essential medicine list policy and decoupling the nexus between medicine sales to health worker remuneration and bonus payments in primary care organisations [ 14].
The point is to drive costs down, do more with less, find out what users consider essential in a mobile device and evolve the Nexus line until it becomes both affordable and attractive to everyone.
Consequently, developing a Nexus representation of explicit phylogenetic networks is essential for the integration of these into SplitsTree.
Over the nexus with critical minerals such as rare earth, gallium and lithium being essential to the clean technologies that are needed to combat climate change [12, 13].
