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Almost all benzimidazoles with different heterocyclic substituents led to essential modification in their physico-chemical, metabolic and pharmacokinetic properties [9].
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2.2 carries through without essential modifications and in particular the characterization of resonant states (2.24) applies.
As rRNA function is essential, modification of rRNA should also be required in all cell types in multicellular organisms.
N-linked glycosylation is an essential modification of secretory and membrane proteins in all eukaryotic cells.
In the cases that the lower amount of sulfur content in gas condensate will be required, some essential modification can be carried out as follows: A larger reactor.
Sulfation is an essential modification of carbohydrates and proteins.
O-GlcNAcylation is an essential posttranslational modification in metazoa.
Sulfation is an essential posttranslational modification in which sulfate groups are added to glycosaminoglycan chains that are covalently linked to core proteins of proteoglycans.
Protein transduction of recombinant transcription factors has been used for reprogramming [3], but proteins produced in bacteria may be mis-folded and lack essential modifications that only occur in mammalian cells, so that their in vivo functionality may be compromised.
Using single point mutations, Ser, but not the predicted Ser, was identified as the essential residue for this modification in vitro.
In eukaryotic tRNAs, it is known that non-essential modifications are required for tRNA stability in the cell (Alexandrov et al, 2006).
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