Sentence examples for essential mediators from inspiring English sources

Toll-like receptors (TLRs) are essential mediators of host immunity.

Group II chaperonins are essential mediators of cellular protein folding in eukaryotes and archaea.

Hypoxia-inducible factors (HIFs) are essential mediators of the cellular oxygen-signaling pathway.

Giannoni E, Buricchi F, Grimaldi G, Parri M, Cialdai F, Taddei ML et al. Redox regulation of anoikis: reactive oxygen species as essential mediators of cell survival.

The signal transducer and activator of transcription (STAT) family proteins are essential mediators of cytokine and growth factor functions.

Chemokines have been described as essential mediators in leukocytes migration to inflammatory sites and to secondary lymphoid organs.

The transcription factors Hypoxia Inducible Factor-1α (HIF-1α) and HIF-2α are essential mediators of the homeostatic responses that allow hypoxic cells to survive and differentiate.

Research in Dr. Farber's laboratory is focused on immunological memory and specifically on memory T cells as essential mediators of protective immunity.

Much research is devoted to the design of synthetic materials modulating the polarization of macrophages, which are essential mediators of the early stages of the inflammatory response.

Despite deep divisions among Iraqis toward the American presence, some like Mr. Hussein saw them as essential mediators, a buffer that prevented simmering conflicts from exploding into violence.

Enzymes of central carbon metabolism are essential mediators of Mycobacterium tuberculosis (Mtb) physiology and pathogenicity, but are often perceived to lack sufficient species selectivity to be pursued as potential drug targets.