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The essential mechanisms responsible for the motility or flux of cells including epithelial cells are mitotic activity, cell active movement, cell-cell and cell-substrate interactions [ 55], [56.
The essential mechanisms responsible for cell migration are mainly a cell density driven pressure passive movement [80] [81] as well as a cell active movement.
The essential mechanisms responsible for the motility or flux of cells including epithelial cells are mitotic activity, cell active movement, cell-cell and cell-substrate interactions [56].
Kakudo et al. evaluated several super p53s for their ability to induce apoptosis in Saos-2 cells and their sequence-specific transcriptional activities on six p53-target genes, but their study did not elucidate the essential mechanisms responsible for the increased ability to induce apoptosis [ 29].
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The UPS is an essential cellular mechanism responsible for the timely degradation of both healthy and damaged or misfolded proteins.
Clearly, a proper balance of the synthesis and breakdown of lipids is essential for reaching metabolic homeostasis, but the mechanisms responsible for controlling these processes are still not fully understood.
Moreover, animals remain essential to extend our understanding of the mechanisms responsible for cancer and to identify, for example, new targets and biomarkers.
Thus, detailed knowledge of pathways, gene enzyme relationships, and subcellular localization of enzymes and pools of lipids and metabolites involved in the synthesis and turnover of glycerolipids is essential to the elucidation of the complex mechanisms responsible for their regulation.
In the previous section we have identified molecular mechanisms responsible for the emergence of essential characteristics of the lamellipodium-lamellum system.
Hemocyte migration toward infection and wound sites is an essential component of insect defense reactions, although the biochemical signal mechanisms responsible for mediating migration in insect cells are not well understood.
It is therefore essential to aim our efforts at trying to ascertain the mechanisms responsible for altering the BBB integrity, and to reduce the process leading to the CNS involvement in SLE.
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