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Thus, we can conclude that the essential localization error in the constant-context conditions did not result from the repetition of stimulus presentations at the same location.
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Previous studies have shown that Baz is essential for localization of Crb and AJ during photoreceptor morphogenesis [6], [7].
This suggested that the C-terminal 44 amino acids contain the region essential for localization of SYT-SSX2 to polycomb complexes.
Although the BteA LRT motif is essential for localization, it is not required for cytotoxicity following transfection (Fig. 5D).
The PB1-mediated Par6 binding is essential for localization and activation of aPKC (Graybill et al., 2012).
Human PTPN22 can be expressed in several isoforms, and some of the isoforms are also present in the nucleus due to at least two essential nuclear localization signals.
We identified novel domains in the N- and C-terminal regions of the protein that are essential for localization, transposon repression, posterior patterning, and pole cell specification.
In addition, the diffuse GFP RAB-3 phenotype was fully rescued when wild-type snt-1 was introduced into mutant animals, suGFP RAB-3that SNT-1 is indeed essential for localization of RAB-3 on SVs.
Additionally, the addition of TBB, a CK2 inhibitor that potentially reduces the PHRF1S915/T917 phosphorylation, impaired the recruitment of PHRF1 to DNA damage sites, indicating that PHD domain and phosphorylatable SDTE motif are essential for localization of PHRF1 to DNA damage sites.
In some cases, these could be clusters of the same motif like the repeated motif UUCAC essential for localization of the Vg1 mRNAs in Xenopus oocytes [ 33] or GCAC motif identified in Xpat mRNA, fifteen copies of which are present in a 526-nt window [ 34].
Imprinted genes present a series of common, though not essential, features: localization within clusters, complex epigenetic regulation, preferential expression in placenta and brain, non-coding antisense RNAs, etc. Up to now, about 150 imprinted genes are known in mice and humans (http://igc.otago.ac.nz; www.geneimprint.com; www.mousebook.org/catalog.php catalog=imprinting).org/catalog.php catalog=imprinting
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