Sentence examples for essential issue is that from inspiring English sources

"The essential issue is that prohibition not only strips us of our personal liberty, but it also funnels billions of dollars to violent criminal organizations.

To achieve that, one essential issue is to per-estimate the activity of different compound against different target proteins.

One challenging and essential question for this issue is that: At least how many nodes should be informed about the objective tracking signal?

Essential revisions: 1) A key issue is that the authors use different cell types to come to their conclusions.

The main issue is that no essential changes had happened to the patients between the two measurements.

Among essential methods criteria, the main issue was that only three (10%%) of the studies used clinical-effectiveness estimates identified through systematic review of the literature.

"The developed countries are trying every means possible to avoid discussion of the essential issue — that is, emission reductions".

My biggest issue with this, however, is that trust is essential in the wedding planning process.

The continuous evaluation of the efficient hospital utilization is an essential issue that must be considered to increase the quality of health care providers.

"It is essential that this issue is adequately addressed if the long-term economic potential for south east Wales, and the whole of Wales, is to be realised".

"The basic and essential issue for us is that all trade barriers be eliminated so that we can have unimpeded, preferential access to the markets of all countries in the region, starting with the American market," Luiz Felipe Lampreia, Brazil's foreign minister, said in an interview.