Sentence examples for essential initiators from inspiring English sources
We next focused our study on Noxa and Puma, because these two proteins are essential initiators of apoptosis.
As chymases contribute to matrix degradation, tissue remodeling and angiogenesis, a new concept emerges, which implies MCs as essential initiators of tissue remodeling during pregnancy.
The BH3-only proteins (Bim, Bid, Puma, Bmf, Bik, Bad, Noxa and Hrk) are essential initiators of apoptosis that cause activation of Bax and Bak, either directly or indirectly by binding to and blocking the prosurvival Bcl-2 family members.
Another recent report [ 17] also confirmed that immune complex and FcγRIII are essential initiators of arthritis through sequential activation of effector cells, thus giving antibodies access into the joint.
2 Its BH3-only members, which include Bad, Bim/Bod, Bik/Blk/Nbk, Hrk/DP5, Puma/Bbc3, Noxa, Bmf and Bid, are essential initiators of apoptosis that are activated in response to distinct developmental cues and cytotoxic signals.
Stress-induced apoptosis mostly involves triggering of the intrinsic cell death machinery, employing BH3-only members of the Bcl-2 protein family as essential initiators of apoptotic cell death.
ZD55-AChE reduced the procaspase 9 protein, which is the essential initiator caspase required for apoptosis signaling through the mitochondrial pathway.
IF2 in bacteria, which is known as eIF5B in eukaryotes and aIF5B in archaea, is an essential initiation factor, promoting initiator tRNA binding to the small ribosomal subunit, and subsequent subunit joining.
The BH3-only proteins Bad, Bik, Bid, Bim, Bmf, Puma and Noxa are essential apoptotic initiators (Danial & Korsmeyer, 2004), yet each of them may respond to particular cellular stressors.
This conserved tRNA modification is essential for stability of initiator tRNA in Saccharomyces cerevisiae.
Results in Figure 7 show that JWH-015 induced activation of caspase 9, which has been described as an initiator caspase essential in the intrinsic or mitochondrially gated pathway of apoptosis (Johnson and Jarvis, 2004; Denault and Salvesen, 2008).
