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The homolog search approach is essential in our study since the porcine genome is not yet available for a direct prediction.
The three major protein translation regulatory pathways of infB, tsf and prfA, as well as translational machinery pathway rpoA were found to be essential in our study.
Also, several gene probes were left out of the core genome analysis due to low hybridization signals or redundancy; two of these are identified as essential in our study.
Bringing the DEG and P. gingivalis core genome together in relation to P. gingivalis gene essentiality, we have determined that 369 genes within the core genome, ones not identified as essential in our study, have BLAST matches to genes within the DEG(Additional file 4: Table S4).
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There are three essential findings in our study.
Association of T variant with the essential hypertension in our study has shown agreement with some studies.
Those two compounds were not observed among the isolated essential oils in our study.
Thus, the essential oil in our study had strong activity than the positive control at doses above 40 mg/Kg.
An essential finding in our study is the strong statistically relationship between SOC and SF-36 mental health dimension for NH residents.
Besides 1,8-cineole, antioxidant activity was determined also for α-pinene, a bicyclic monoterpene that is present in the studied essential oil in our study in a relatively high amount (11.51%), and this compound could contribute to hepatoprotective activity of REO as well [ 38].
The chemical profile of the mango essential oils in our study, characterized by a high quantity of monoterpenes, was very similar to that reported for samples collected in different regions of the world [ 8, 9, 36, 37].
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