Case III considers two parallel pathways, either one of which can supply an essential product; simultaneous impairment of both pathways is lethal.
The oxytocin receptor (OXTR) gene has been implicated as a risk gene for autism spectrum disorder (ASD)—a neurodevelopmental disorder with essential features of impairments in social communication and reciprocal interaction.
We aimed to determine whether distress and impairment, considered essential characteristics of mental disorders, could be explained by experiences of social rejection and violence rather than being inherent features of transgender identity, and to examine the applicability of other elements of the proposed ICD-11 diagnostic guidelines.
Therefore, protein misfolding is usually associated with the impairment of essential cellular processes.
Measurement of children's development, behaviour, and impairment is essential in studies that seek to determine the impact of early life events on functional abilities.
Assessment of neurocognitive impairment is essential but difficult because it is generally not detected by imaging and other routine diagnostic methods [ 22], and deficits may be present in seemingly neurologically intact patients.
The memory impairment, still essential for the new revised research criteria in association with CSF or imaging biomarkers for the diagnosis of AD [ 105], is not always the prominent early deficit.
Thus, the maintenance of a healthy mitochondrial population is essential to avoid the impairment of the processes they regulate: for this purpose, cells have developed mechanisms involving a complex system of quality control to remove damaged mitochondria, or to renew them.
The research project PROMPT, focussing on pedestrian comfort needs, shows the importance of considering individual characteristics such as age, gender and state of health, especially in the connection with mobility impairments, as essential factors for assessing comfort.
