Sentence examples for essential functional group from inspiring English sources

The circular dichroism spectra of the D32A variant varied by only 3.6% at 220 nm confirming that an alanine replacement of the active site Asp does not affect the conformation significantly and therefore the mutation results only in the loss of an essential functional group acting as a base in the phosphate-transfer reaction.

Synthesis of serine derivatives having the essential functional groups for the inhibitor of SARS 3CL protease and evaluation of their inhibitory activities using SARS 3CL R188I mutant protease are described.

This analysis reveals how conserved nucleotides within the two internal loop motifs establish the architecture of the macromolecular interface and position essential functional groups for direct recognition by the protein.

Conversely to the anthocyanins, betalains possess essential functional groups (–COOH) to anchor better to the TiO2 nanoparticles than the functional groups (–OH) present in anthocyanins [10, 11, 12, 13].

Our investigations have confirmed the results of the X-ray structure and disproved the old pharmacophore model for progestogenic activity, comprising two essential polar functional groups on both ends of the steroid core.

We have found that there are specific functional group characteristics that are essential for the activities of these molecules.

The developed approach for improving control of functional group distribution in microgels is essential for the design of more advanced microgel structures for specific applications.

In an irreversible inhibition, the inhibitor combines with or destroys a functional group on the enzyme that is essential for its activity.

Since the cyclic by-product has no functional group for further crosslinking, it is essential to determine its presence and amount in the reaction mixture.

To have a better picture of the roles of different essential genes, multi-functional genes were categorized into more than one functional group.

The α, β-unsaturated carbonyl group in zerumbone was found to be essential for its bioactivity as zerumbone analog α-Humulene that lacks this functional group, could neither radiosensitize CRC cells, nor deplete cellular GSH.