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This culture of disputatiousness does yield some essential fruits.
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One-third of evolutionary young genes is essential to fruit flies.
A homologue of mazF toxin called mazF-mx is essential for fruiting body formation in Myxococcus xanthus.
Anthocyanin biosynthesis is essential for fruit coloration.
Two of these transcription factors were already shown to be essential for fruiting body formation, namely mcm1 and pro44.
From an agricultural point of view, proper floral organ and gamete formation is essential for fruit development following fertilization.
The pro41 gene that encodes an ER membrane protein essential for fruiting body formation (Nowrousian et al. 2007a) is also down-regulated in the sec22 mutant.
pro44 orthologs have been characterized in A. nidulans, N. crassa, and A. fumigatus, where they were shown to be essential for fruiting body formation (Colot et al. 2006; Han et al. 2001; Szewczyk and Krappmann 2010).
Previously, we showed that the pro11 gene of S. macrospora encodes a protein of the striatin protein family that is essential for fruiting body development (Pöggeler and Kück 2004).
Comparative genome analysis identified a total of 73 genes of which two encoding an unknown C2H2/ankyrin protein and a homolog of the WD-protein HAM5 were identified to be essential for fruiting body formation.
The two mating-type genes Smta-1 and SmtA-2 that are essential for fruiting body formation (Klix et al. 2010; Pöggeler et al. 2006b) are slightly down-regulated in the sec22 mutant, although only expression of Smta-1 is significantly different from the wild type.
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