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Mechanoelectrical transduction (MeT) channels embedded in neuronal cell membranes are essential for touch and proprioception.
Transformation of mechanical energy into ionic currents is essential for touch, hearing and nociception.
Disruption of microtubules in the TRNs also reduces expression of proteins essential for touch sensitivity, including MEC-2 and MEC-18 (Bounoutas et al. 2009, 2011).
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Although putative mechanosensitive ion channels have been proposed, none have been identified as essential for pain or touch.
Artem Stepanov (@meisographic) has a similarly captivating video of oval drills (just what it sounds like — the ovals are "essential for developing a light touch").
I don't claim that size reduction alone accomplished all this, just that size reduction is essential for putting employees in touch with one another so they can coordinate their work.
Loss-of-function of epg-1, bec-1, lgg-1, and epg-6 reduces degeneration of touch neurons caused by mec-4 gain-of-function mutations, 5,8,9,15, indicating that autophagy activity is essential for the necrotic death of touch neurons.
The computer games developer - behind, until the end of last year, Championship Manager as well as the recently launched NHL Eastside Hockey Manager - believes blogs are essential for companies wanting to stay in touch with their public.
In 1979 he wrote: "So heavy was my anguish that I made a vow: not to speak, not to touch upon the essential for at least ten years.... Long enough to regain possession of my memory.
NOMPC is a TRPN channel essential for adult hearing and larval gentle touch (Gong et al., 2004; Yan et al., 2013).
This wall sustains an extreme internal pressure of 150 bar in stenotele nematocysts (Weber 1989), which discharge upon touch and are essential for predation and defense in Hydrozoa.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com