In vivo, RNA replication was essential for the induction of an immune response.
Besides the indirect effects on the survival and function of T cells through autophagic proteins, autophagy also showed a direct role in antigen presentation to antigen-specific T cells (a process essential for the induction of acquired immunity) [41].
Besides the predominant role of B cells during this process, the importance of T cell response is evident: T cells are essential for the induction of high-affinity antibodies and immune memory.
Such activation is essential for the induction of innate immune responses.
Spine and dendritic calcium dynamics are essential for the induction of synaptic plasticity [4].
Hence, the complete sequences of CHR and CAT appear to be essential for the induction of the transient Ca2+ influx.
Consequently, the development of a novel vaccine adjuvant is essential for the induction of cell-mediated immunity.
In influenza virus infected human lung cells, p53 is shown to be essential for the induction of apoptosis and its inhibition resulted in elevated virus replication [15].
The pgr5 mutant is defective in PSI cyclic electron transport, which is essential for the induction of NPQ via its role in generating ΔpH [9].
The T4SS is essential for the induction of an early and severe corpus inflammation, associated with an increased expression of cytokines and histopathological changes.
Previously, direct interactions between Eya1 and Six1 have been shown to be essential for the induction and upregulation of Gdnf expression in the MM [26], [35].
