It has been suggested that the motor system overcomes this problem by identifying those parts of a task that are essential for achieving the end goal, and then focusing resources on reducing the variability in the performance of those parts alone.
Yes, and essential for the tail end of August when my family makes what has become an annual pilgrimage to Pawleys Island, a fragile spit of an island off the coast of South Carolina.
LIG4 is essential for the nonhomologous end joining (NHEJ) of DNA following double strand breaks [Grawunder et al., 1998a].
CF IA furthermore contains Rna14, Pcf11 and Clp1, which are all essential for the 3′ end processing and termination reactions.
Mutational analyses of an Flt-1 minigene construct revealed that two non-contiguous AUUAAA sequences act as the poly(A) signal and that a U-rich region 24 nucleotides downstream of the major cleavage site is essential for the 3′-end processing of sFlt-1 mRNA.
Moreover, we have found that phosphorylation of RPA2 is specifically required for HR in response to replication arrest, but is not essential for the cutting two-end DSBs induced HR [ 23].
Such an agreement should remain a goal, but is not essential for ending the current impasse.
Exciting new evidence demonstrates that migratory white blood cells, macrophages and eosinophils, are drawn to the vicinity of the end bud by chemoattractants and, surprisingly, prove to be essential for the normal development of end buds [ 9].
At cellular telomeres, TRF2 is essential for the protection of chromosome ends from double-strand break repair and end-to-end fusions [29], [30].
While the ability to access the models is essential for end users, executing the PI models on personal computers, in most cases, may not be feasible due to the computational complexities of the models.
