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Staudt, V. et al. Interferon-regulatory factor 4 is essential for the developmental program of T helper 9 cells.
Developing the placental vasculature is essential for the developmental homeostasis of the placenta and fetus.
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The cellular volume of the oocyte contains critical maternal products that are essential for supporting the developmental events of meiosis, fertilization, and early embryo development.
Therefore, reducing stress by taking into account the physiology of the embryo is essential for the maintenance of developmental competence in vitro.
In the nematode, Caenorhabditis elegans, two of the earliest events following fertilization are secretion of the chitinous eggshell and completion of meiosis, and in this report we demonstrate that the eggshell is essential for multiple developmental events at the one-cell stage.
Though NRP1 is essential for developmental angiogenesis, the contribution of the NRP1-VEGF interaction to physiological or pathological angiogenesis is unclear.
Specificity and precision of expression are essential for the genes that regulate developmental processes.
In agreement, during neuronal differentiation MSL is essential for the regulation of key developmental genes.
Our most recent studies have shown DG is expressed in radial glia during neocortical histogenesis, and that glial DG is essential for multiple developmental processes, including maintenance of the basement membrane integrity, normal radial glia morphology, organization of neocortical proliferation, and cortical plate lamination [ 8].
Methodologies for the rigorous and quantitative evaluation of biological activity or potency are an essential aspect of the developmental pathway for all biologic product candidates.
Planar cell polarity (PCP) in epithelia, orthogonal to the apical-basal axis, is essential for numerous developmental events and physiological functions.
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