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Finally, we show that the BD of BRD9 is essential for targeting BRD9 to chromatin and affecting gene expression.
Internet tracking is also essential for targeting ads delivered by the big advertising networks, and without such cookies sites relying on these for revenue could be adversely affected.
Altogether, our data demonstrate that the BD is essential for targeting BRD9, and is required for BRD9's role in gene expression.
Our findings support that focus on headache frequency and intensity is essential for targeting a subgroup of migraine patients at risk of developing MOH.
This information, she says, is essential for targeting existing tools, social and behavior change interventions and the development and deployment of prevention tools to complement bed nets and indoor spraying.
A lack of understanding of the molecular basis of this inhibition has been a major bottleneck in the development of next generation of drugs essential for targeting the mycolic acid component of mycobacteria.
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In addition, Opekarová et al. demonstrated that PtdEtn is an essential factor for targeting Can1p to the plasma membrane of yeast (Opekarova et al., 2002).
These results are consistent with previous studies which demonstrated that the miRNA-target RNA interaction is restricted to the 5'-end of the miRNA sequence and that the perfect complementarity between the miRNA 2 8 bases and the targeted RNA is essential for target recognition [30] [33].
Ayton, P.M., Chen, E.H. & Cleary, M.L. Binding to nonmethylated CpG DNA is essential for target recognition, transactivation, and myeloid transformation by an MLL oncoprotein.
According to computational and biochemical analyses [5] [7], [12], seed nucleotides are essential for target gene recognition and repression.
Experimental results show that Anidu FlbB G70 residue is not essential for target DNA recognition in vitro but seems to be necessary to increase the efficiency of the binding.
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