Sentence examples for essential for its function from inspiring English sources

Although the SUB kinase domain is not essential for its function in vivo it is possible that phosphorylation of SUB by as yet unknown kinases is important.

The role of Neuropilin-1 is an important piece of the puzzle in VEGF signaling, and the central dogma about Neuropilin-1 is that binding to VEGFA is essential for its function despite lacking direct evidence to support it.

To understand how nodal function may be disrupted in disease, we need to understand the electrical principles by which the node operates, how it is formed and the molecules which are essential for its function.

Preclinical studies have demonstrated that localization of KRAS to the plasma membrane is essential for its function.

Intramembrane mobility and clustering of Env trimers at the viral budding site are essential for its function.

These results demonstrate that the position of the DNA flap is not essential for its function in the context of HIV-1-derived lentiviral vectors.

However, previous reports suggest that a cysteine residue in position 81 of EF-Tu from Escherichia coli is essential for its function.

In this way, miR-130a could serve to buffer changes in MeCP2 protein expression and may help maintain MeCP2 at an appropriate level, which is essential for its function.

Altogether, these results support our hypothesis that Sdo1p is a dynamic probe of the maturation status of the 60S subunit, and the inter-domain flexibility of Sdo1p/SBDS is essential for its function.

This precise property, which is essential for its functions, also makes it very dangerous, because free iron can catalyze the formation of free radicals that can damage the cell.

Phosphorylation of Smp1 is essential for its functioning, since an allele unable to be phosphorylated caused an impaired stress response [ 30].