Sentence examples for essential for commitment from inspiring English sources

The p38, on the other hand, is essential for commitment of mouse ESCs into mesodermal lineages that lead to cardiac, endothelial, smooth muscle, and skeletal muscle differentiation, but inhibits early neural differentiation.

While the transcription factors Runx2, and Osterix (OSX) have been shown to be essential for commitment to the osteoblastic lineage, few factors that play a defined role in early osteoblast lineage expansion have been identified (15- 19).

The pre-publication history for this paper can be accessed here: http://www.biomedcentral.com/1471-2288/9/63/prepub Diabetes cardiovascular risk-evaluation: targets and essential data for commitment of treatment (DETECT) is a cross-sectional and prospective-longitudinal, nationwide clinical epidemiological study.

DETECT (Diabetes Cardiovascular Risk-Evaluation: Targets and Essential Data for Commitment of Treatment) is a large nationally representative epidemiologic cross-sectional and prospective longitudinal study in German primary care settings [ 14, 15].

More recently the Diabetes Cardiovascular Risk Evaluation: Targets and Essential Data for Commitment of Treatment (DETECT) Germany-wide study conducted in 2003 and including 8,188 type 2 diabetes patients reported that 50% of patients had at least one diabetes complication and 34% had macrovascular complications [ 6].

"We think it's essential for that commitment to be shown.

The E2A transcription factors are essential for the commitment and differentiation of B- and T-lymphocytes [23].

In BM, the deficiency of the canonical Notch signaling led to the reduction of EPC, but a substantial fraction of EPC exists, suggesting that the Notch-RBP-J pathway is not essential for EPC commitment.

Mbd3 function was reported to be dispensable for ES cell growth in culture, but essential for their commitment to a full spectrum of embryonic lineages when aggregated with wild type embryos, indicating pluripotency of these cells is indeed affected [15], [32].

GATA4 is also a potent cardiogenic factor essential for cardiomyocyte commitment and differentiation.

In this context, the faithful transmission of this epigenetic signature to daughter cells is essential for lineage commitment.