Sentence examples for essential for bone development from inspiring English sources

More recently, Kim et al. demonstrated that upregulation of ROS inhibits osteogenic differentiation of MSCs, in part through inhibition of the Hedgehog (Hh) signaling pathway, which is essential for bone development and maintenance (Kim et al., 2012).

Likewise, in bone, miRNAS target genes were found associated with functions essential for bone development and remodeling, as well as bone cell differentiation and activation.

In addition, LRP5 also plays a pivotal role in blood lipid metabolism and blood glucose, resulting in prevention of decreased bone formation; thus LRP5 is essential for bone development and health [ 17, 18].

Therefore, these results suggest that osteoblastic cells arising from BM concentrate exhibit a normal behavior regarding paracrine pathways of osteoblast/osteoclast communication, which are essential for bone development and remodeling.

There is some evidence that oral estrogen administration is associated with the suppression of IGF-1 production by the liver and of androgen levels, which are also essential for bone development [ 121, 122].

High molybdenum intake is known to cause secondary deficiency of copper, an essential element for bone development (Arthur 1965).

Relative to kinky Afro-textured hair, straight hair allows more UV light to pass to the scalp (which is essential for the production of vitamin D, that is important for bone development).

Also required for bone development.

The various cell types populating the bone marrow extensively communicate with each other, and cell-to-cell cross talk is likely to be essential for proper bone development and homeostasis.

RUNX2 is a key transcription factor in osteoblast differentiation, essential for mammalian bone development.

Bioavailable estradiol level is now believed to be a determinant of bone mass and its action essential for normal bone development (Orwoll 2003).