Sentence examples for essential fate from inspiring English sources

For instance, the model predicts the transient expression of the genes Ngn3 and Pax4 which disappear in the mature cells despite being essential fate determining factors for endocrine cells.

It is therefore essential that its fate and transport in the environment be assessed before its large scale implementation.

As these nano-containing products transition through their life cycle, it becomes essential that the fate of the nanoparticles is investigated and any potential risks are assessed.

The mechanical microenvironment of bone has the potential to regulate osteogenic lineage commitment by initiating multiple key molecular pathways that are essential for cell fate commitment.

Since the Dll4-Notch1 signaling pathway is essential for arterial fate specification, our data strongly suggest that Mib1 is the E3 ligase that regulates Dll4 activity in endothelial cells.

The Notch signaling pathway is an evolutionarily conserved intercellular signaling module essential for cell fate specification that requires endocytosis of Notch ligands.

Activation of DNMT3A and DNMT3B during embryonic development establishes the DNA methylation pattern, which is essential for cell fate determination, as well as gene imprinting and X-chromosome inactivation [3], [4].

During development secreted proteins are essential for cell fate specification and cell migrations.

On the other hand, the repression of extrinsic signals is essential for neural fate commitment.

Interestingly, both rod and cone photoreceptors share several key genes essential for cell fate specification and differentiation.

It is known that the integrity of TCR signaling is essential for the fate of developing thymocytes.