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Thus, this review is focused on the analysis of molecular characteristics, potency (equilibrium dissociation constants, binding activity, and biological potency) and effector functions of mAb candidates (Fig. 1), and will also discuss the essential evaluations of mAbs as biosimilar therapeutics.
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If interventions designed to change antibacterial drug use behaviour are implemented, baseline data on use and resistance will be essential for evaluations of the effectiveness of those interventions.
Assessment of ER stress is also essential for evaluation of therapeutic drugs in vitro and in vivo; that is, their therapeutic utility as well as adverse effects.
Mice are extensively used for gene modification research and isolated cardiomyocytes are essential for evaluation of cardiac function without interference from non-myocyte contribution.
However, experimental verification is still essential for evaluation of processability and related concomitant phenomena, such as possible solid state changes that may occur during production and storage.
Noninvasive small animal imaging techniques are essential for evaluation of cardiac disease and potential therapeutics.
The definition of target earthquakes is essential for evaluation of models.
In addition, IVDR offers an accurate measure of driving exposure level, which is essential for evaluation of the risk of being involved in road crashes [12].
Also, heartbeat auscultation is essential for evaluation of fetal vitality and subsequent conduct [ 52].
Physical exam was essential for evaluation of sinonasal mucosa, leading in some cases to deferment of the planned eTSA.
A complete and detailed insight in the applied decision rules in these approaches is essential for evaluation of HOS.
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