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The ability to manipulate ligand-induced conformational change, although representing a major challenge to the protein engineer, is an essential end point in efforts to produce novel functional proteins for biotechnology and therapeutic applications.
"There are different forms of ice," Ms. McEwen explained, and while every cube of ice has the same essential end point — and a purpose little understood in countries like, say, England or France — its use can be manipulated, ice experts say, to improve the quality of the drink it cools.
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In the setting of neoadjuvant clinical trials, histopathologists are a vital part of the trial as thorough specimen handling and accurate histological reporting is essential to correctly assess the primary end point (Sahoo and Lester, 2009).
Our study is, as far as we know, the first randomised, controlled trial to assess, as the primary end point, risk in essential hypertensive patients for new onset of diabetes associated with treatment by thiazide diuretics.
Determining the degree of correlation of the surrogate end point to the clinical benefit end point is essential in assigning a value to its inclusion in a proof-of-concept study in drug development.
The end point is July 31 , 2008
The future and end point for devolution.
Note, no end point is achieved.
You have a definite end point.
This suggests tight quantitative end point control.
End point selection.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com