Sentence examples for essential challenge to from inspiring English sources

That's because to do so captures Egan's essential challenge to herself: How wide a circumference can she achieve in "A Visit From the Goon Squad" while still maintaining any sort of coherence and momentum?

Therefore, the development of reliable short-term forecasts constitutes an essential challenge to minimizing and managing risks.

Designing and evaluating such systems remain essential challenges to researchers and practitioners.

Although no consistently reliable algorithm is currently available, the essential challenges to developing a general theory or approach to protein structure prediction are better understood.

The essential challenge is to minimize the I/O operation as much as possible such that queries can be answered more efficiently.

Assuring functional safety and IT security is rapidly becoming an essential key challenge to the design of any connected smart product and industrial manufacturing system.

This is an essential challenge that needs to be addressed by robust study designs including normal and non-progressing controls when known to be appropriate.

It's about changing direction from the past eight years, and on that essential challenge, John McCain has nothing to say.

A mechanistic interpretation of the multi-staged aggregation process and a structural characterization of key intermediates therefore pose an essential challenge, also with regard to the identification and application of therapeutic strategies interfering with non-native peptide and protein aggregation.

Indeed, the essential challenge in fluid therapy is to avoid the administration of too little or too much volume, since there is a relatively narrow range for safe fluid therapy and both overload and underhydration can adversely affect the patient outcome.

This necessary omission of something essential was the challenge to commissioning and editing Adventures Less Ordinary: How to Travel and Do Good, a new and free guide to mindful adventures due to be released in mid-January and drawing on the combined expertise of two dozen leading voices advocating for travel that makes a difference.