An understanding of noncovalent interactions in ligand receptor complexes is essential for the appreciation of drug action mechanisms as well as for rational drug design.
While this can be conducted in a rigorously empirical manner, an essential step is appreciation of the inextricable enfolding or interdependent co-creation of mind and world, a step that was excluded throughout the development of modern science over the last several centuries.
Composers may even intend "spatial gestures" among aspects essential for the appreciation of a piece (see, e.g., Solomon 2007).
The distinction marks a crucial division between those positions that take knowledge and information to be essential to aesthetic appreciation of environments and those that take some other feature, such as engagement, emotion arousal, or imagination, to be paramount.
This is essential for optimal appreciation of allele specificity found within next-generation sequencing data.
Consideration of additional locations and time points is thus essential for full appreciation of the nematode's natural ecology.
Building personal relationships is essential, and an appreciation of customs and social mores fundamental to establishing researcher credentials and acceptability within the group.
Thus, understanding the control of the expression of the dicer gene is essential for the appreciation of double-stranded (ds)RNA-mediated pathways of gene expression.
Despite the challenges involved in experimental manipulation of species with complex life histories, such research is essential for full appreciation of the biological effects of climate change.
The great challenge for economists today is to find new and better ways to make their cases, with the goal of kindling a general appreciation of essential economic ideas such as incentives, trade-offs, marginal utility and revealed preferences.
The case is made that the triadic semiotic framework is essential for a complete appreciation of the constructs that were central to Rasmussen's approach: Abstraction Hierarchy, Skill-Rules-Knowledge Model, Ecological Interface Design, and Proactive Risk Management.
