Sentence examples for essential and major from inspiring English sources

With respect to the oxaliplatin-induced cold hypersensitivity, TRPA1 does not seem to play a major role, confirming the essential and major contribution of TRPM8 expressing fibres in this phenomenon.

At the molecular level, the epidermal growth factor receptor (EGFR), the cell adhesion molecule E-cadherin, and transcription repressors of E-cadherin such as SNAIL and SLUG have been shown to play essential and major roles in EMT and development of invasive and metastatic bladder cancer [ 6].

To be sure, all advanced nations need a strong tax base for their essential services and major investments in the future.

The renin-angiotensin system is a major endocrine/paracrine system that regulates blood pressure (BP) in our body [ 49], genes encoding components of this system have been strong candidates for the investigation of the genetic basis of essential hypertension and major targets for antihypertensive drugs [ 50].

Glutamate and glutamine, the essential biomass components and major intracellular nitrogen donors, are the products of ammonia assimilation and are synthesized in bacteria via two pathways [ 34].

Storage will be essential and play a major role in the future.

I would love to see stand-alone underwater skyscrapers anywhere they might work, but especially along the African coastline where fishing is essential and overfishing a major problem.

Concentration data on some toxic elements and major essential elements in breast milk in women from different countries, based on different analytical techniques, have been published since then [ 5- 11].

Thus, America's largest tech companies quickly banded together to demand greater transparency about the scope of surveillance – an essential safeguard against any abrupt and major expansion of collection.

To be successful in marketing a Product Category One device it is essential to understand the patterns and major players in the industry.

A qualitative test indicated the presence of saponins and chromatographic analysis revealed the presence of steroids, alkaloids, terpenoids, saponins, amino acids, phenolics, flavonoids and essential oil as major phytochemicals and the absence of the sapogenins following the application of different solvent systems and spraying reagents.