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Essential agreement for both the methods was 100% with the Etest method (tables 2 and 3).

The complete per cent agreement of penicillin for the CDS and CLSI method with Etest was 91.5% and 87.5%, respectively, and the essential agreement for both was found as 100% (tables 2 and 3).

In a previous study evaluating Vitek 2, essential agreements with nitrofurantoin were 93.7%% for staphylococci and 88.9 % for enterococci [ 25], indicating that susceptibility testing for nitrofurantoin may be difficult for automated instruments.

Comparison of the LC and CC results showed good Essential Agreement (90.3% for Etest and 92.9% for Sensititre), and even higher Categorical Agreement (93.9% for Etest and 96% for Sensititre); differences were observed according to the species, method, and antifungal drug.

The essential agreement between the CLSI-d2 method and the EUCAST-d2 method was 38%to61%1% and lowest for isavuconazole.

The overall essential agreement within ± 1 doubling dilution between standard BMD method and Etest method was 100% for vancomycin and 73.1% for daptomycin.

The essential agreement was highest for Lichtheimia corymbifera (100% across amphotericin B, posaconazole, and isavuconazole and 7/8, 88%, for voriconazole) and lowest for amphotericin B against Rhizopus oryzae (1/6, 17%), isavuconazole against Rhizopus microsporus (14/26, 54%), and posaconazole against Mucor circinelloides group II (3/7, 43%) and Rhizomucor pusillus (5/8, 63%).

The percent essential agreement (±1 2-fold dilution) between the EUCAST and the CLSI methods was calculated for each species.

LK We can end in essential agreement then.

The best essential agreement was found between the CLSI-d2 method and the EUCAST-d1 method, with overall essential agreement ranging from 75% for isavuconazole to 83% for amphotericin B. The median (range) 2-fold dilution differences were 0 (−3 to 4) (Table 2).

The overall essential agreement was 95%% (57 of 60).

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